Beta-lactam allergy in the paediatric population
نویسندگان
چکیده
منابع مشابه
Genetic associations in beta-lactam allergy
Immediate reactions to beta-lactams (BLs) are the most common allergic reactions against drugs and can be lifethreatening. The genetic risk factors influencing these reactions are poorly known, except those which were previously identified as predictors of atopy and inflammation. Two polymorphisms of nucleotide-binding oligomerization domain 2 (NOD2), a gene associated with chronic inflammatory...
متن کاملThe Survey of Genes Encoding Beta-Lactamases, in Escherichia Coli Resistant to Beta-Lactam and Non-Beta-Lactam Antibiotics
Objective(s) Resistance to the new generation of cephalosporins which is mediated by Extended-Spectrum beta-lactamases (ESBLs) has been found among Escherichia coli isolates throughout the world. These resistance genes and their producers, the micro-organisms carrying beta-lactamases, are responsible for serious clinical and therapeutic problems among inpatients and it is necessary to pay more...
متن کاملPD32 - Non-immediate type beta-lactam allergy in childhood
Material and method A prospective study was performed using ENDA questionnaire in 103 children [4.8 (2.7-7.9) years, 60% male] with 124 non-immediate type hypersensitivity reactions. Prick and intradermal skin testing with major/minor determinant mixture, penicilin G, ampicillin, amoxicillinclavulanate and the culprit drug were done. In patients with negative skin tests, patch and intradermal t...
متن کاملDesensitization in patients with beta-lactam drug allergy.
BACKGROUND Patients with a history of beta-lactam antibiotic allergy are often admitted to the hospital with severe or life-threatening infections requiring beta-lactam antibiotics. Strict avoidance of beta lactams to such patients may prevent them from getting adequate coverage and can lead to an increase in the use of alternative antibiotics, which can predispose to antibiotic resistance. Pas...
متن کاملPrevalence of beta-lactam allergy: a retrospective chart review of drug allergy assessment in a predominantly pediatric population
BACKGROUND Research suggests that 90% of patients labeled beta-lactam allergic are able to tolerate penicillins following further assessment. This study aims to define and describe the frequency of true beta-lactam allergy following allergy patient evaluation in a predominantly pediatric population. METHODS 306 primary care patients referred between January 2010 and June 2015 were assessed fo...
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ژورنال
عنوان ژورنال: Paediatrics & Child Health
سال: 2020
ISSN: 1205-7088,1918-1485
DOI: 10.1093/pch/pxz179